NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which opioid is noted for having a risk of medication error with its high-potency injection?

Hydromorphone
Codeine
Fentanyl
Methadone

The correct answer is: Hydromorphone

Hydromorphone is noted for having a risk of medication error with its high-potency injection. Hydromorphone is significantly more potent per milligram compared to other opioids like morphine. Therefore, administering hydromorphone without being aware of its potency can lead to serious overdose or adverse effects. This high potency increases the risk of medication errors, making it a critical concern in healthcare settings. In contrast, codeine, fentanyl, and methadone are opioids with different potency levels and characteristics, but they are not specifically known for having the same high risk of medication errors with their injection as hydromorphone.