NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which drug is a preferred antidepressant in patients with QT/Cardiac risk?

  1. Nortriptyline

  2. Sertraline

  3. Duloxetine

  4. Venlafaxine

The correct answer is: Sertraline

Sertraline is a preferred antidepressant among patients with QT/cardiac risk due to its relatively low risk for QT prolongation and interactions with cardiac medication. Nortriptyline (A) has a moderate risk for QT prolongation and may interact with cardiac medication. Duloxetine (C) and Venlafaxine (D) both have a higher risk for QT prolongation and interactions with cardiac medication, making them less preferred options for patients with cardiac risk.

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