NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the initial treatment duration for a diabetic foot infection without MRSA coverage needed?

3-5 days
7-14 days
2-4 weeks
4-6 weeks

The correct answer is: 7-14 days

For a diabetic foot infection without MRSA coverage needed, the initial treatment duration is typically 7-14 days. This time frame is suitable for targeting common pathogens involved in diabetic foot infections while providing adequate time for the infection to respond to therapy. Shorter durations such as 3-5 days may not be sufficient to fully resolve the infection, while longer durations such as 2-4 weeks or 4-6 weeks may increase the risk of antibiotic resistance development and adverse effects without significant added benefit for uncomplicated infections. Therefore, the most appropriate initial treatment duration for a diabetic foot infection without MRSA coverage is 7-14 days.