NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Natalizumab carries a boxed warning for which condition?

  1. Liver damage

  2. PML

  3. Heart failure

  4. Severe infections

The correct answer is: PML

Natalizumab carries a boxed warning for progressive multifocal leukoencephalopathy (PML). PML is a rare but serious brain infection caused by the JC virus. This warning is included due to the risk of developing PML while taking Natalizumab. Liver damage, heart failure, and severe infections are not the specific boxed warning associated with Natalizumab.