NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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How is a pack-year smoking history calculated?

Cigarette packs/day x years smoked
% risk in control group - % risk in treatment group
Cost of new treatment / Effect of old treatment
Hazard rate in treatment group / hazard rate in control group

The correct answer is: Cigarette packs/day x years smoked

A pack-year smoking history is calculated by multiplying the average number of packs of cigarettes smoked per day by the number of years the person has smoked. This calculation helps quantify the amount of smoking exposure a person has had over their lifetime, taking into account both the intensity (packs/day) and duration (years) of smoking. This information is important in assessing the risk of developing smoking-related diseases such as lung cancer and chronic obstructive pulmonary disease (COPD). Options B, C, and D are incorrect as they do not relate to the calculation of pack-years for smoking history. Option B refers to calculating the absolute risk reduction between control and treatment groups in a study. Option C involves comparing the cost and effectiveness of different treatment approaches. Option D pertains to comparing hazard rates between treatment and control groups in a clinical trial.