NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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For febrile neutropenia, what is the threshold oral temperature to initiate empiric antibiotics?

  1. > 37.8 C (100F)

  2. > 38.3 C (101F)

  3. > 38.5 C (101.3F)

  4. > 39 C (102.2F)

The correct answer is: > 38.3 C (101F)

The threshold oral temperature to initiate empiric antibiotics for febrile neutropenia is > 38.3 C (101F). This is because a higher fever, such as those indicated in options C and D, may indicate a more severe infection that requires immediate medical attention. Option A, > 37.8 C (100F), is incorrect as it falls within the normal range of body temperature. It is important to initiate antibiotics promptly when a patient with febrile neutropenia develops a fever to prevent potentially life-threatening complications.