NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Esketamine (Spravato) is indicated for:

Common cold symptoms
Epilepsy
Treatment-resistant depression and depression with suicidality
Migraine headaches

The correct answer is: Treatment-resistant depression and depression with suicidality

Esketamine (Spravato) is indicated for the treatment of treatment-resistant depression and depression with suicidality. It is a nasal spray medication that acts as a glutamate receptor modulator. This medication is specifically approved for patients who have not found relief with other antidepressant treatments. Options A, B, and D are incorrect because Esketamine is not indicated for the treatment of common cold symptoms, epilepsy, or migraine headaches.