NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Dupilumab, an eczema treatment, is mainly what type of medication?

  1. IL-4 antagonist

  2. JAK inhibitor

  3. Calcineurin inhibitor

  4. Antihistamine

The correct answer is: IL-4 antagonist

Dupilumab is classified as an IL-4 antagonist, which means it works by blocking the activity of the IL-4 receptor. This helps to inhibit the inflammatory response associated with eczema. The other options, while they may be used to treat eczema, are not considered the main type of medication for this condition. JAK inhibitors, for example, are more commonly used to treat autoimmune conditions such as rheumatoid arthritis. Calcineurin inhibitors are typically used as a second-line treatment for eczema after topical steroids have been tried. Antihistamines, on the other hand, are used to relieve itching and are not considered a main treatment for eczema.