NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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A major side effect common among SSRIs is:

Sexual side effects
Increased appetite
Weight loss
Muscle rigidity

The correct answer is: Sexual side effects

SSRIs (Selective Serotonin Reuptake Inhibitors) are medications commonly used to treat depression, anxiety disorders, and certain other conditions. One of the major side effects associated with SSRIs is sexual side effects. These may include decreased libido, delayed ejaculation, erectile dysfunction, or other issues related to sexual function. It is important for healthcare providers to assess and monitor for these side effects when prescribing SSRIs to patients. Options B, C, and D are not major side effects commonly associated with SSRIs. Increased appetite and weight gain are potential side effects of some antidepressant medications, but not typically SSRIs. Muscle rigidity is not a common side effect of SSRIs.