NAPLEX Practice Exam 2026 – All-in-One Guide to Mastering the North American Pharmacist Licensure Examination!

Both Mycophenolate mofetil and Azathioprine are known to inhibit T and B lymphocyte proliferation by altering purine nucleotide synthesis. Mycophenolate mofetil inhibits the enzyme inosine monophosphate dehydrogenase, which is important in purine synthesis. Meanwhile, Azathioprine is converted to 6-mercaptopurine, which also affects the production of purine nucleotides. Tacrolimus, on the other hand, works by inhibiting the production of cytokines and has a different mechanism of action compared to Mycophenolate mofetil and Azathioprine.