NAPLEX Practice Exam 2026 – All-in-One Guide to Mastering the North American Pharmacist Licensure Examination!

When taking PDE-5 inhibitors under certain conditions, such as when a patient is also using certain medications like ritonavir, it is recommended to reduce the dosage of the PDE-5 inhibitor by 50%. This reduction helps to avoid potential interactions between the medications and minimize the risk of adverse effects. It is crucial to adjust the dosage to ensure the safety and effectiveness of the treatment. Therefore, reducing the dosage is the correct choice in this scenario.

The other options are not directly related to the interactions between PDE-5 inhibitors and certain medications or conditions. Reducing the frequency of use, the duration of use, or the number of different PDE-5 inhibitors used may not address the specific concern of potential drug interactions necessitating a dosage adjustment.