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Ibuprofen is not a treatment for Poison Ivy, Oak, and Sumac. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is typically used to reduce pain, inflammation, and fever. While it can help alleviate symptoms like itching and discomfort associated with Poison Ivy, Oak, and Sumac rashes, it does not directly treat the rash itself.

On the other hand, the other options listed are commonly used treatments for Poison Ivy, Oak, and Sumac rashes:

- Aluminum acetate is an astringent solution that can help dry oozing blisters.

- Colloidal oatmeal can be used in baths or topical preparations to soothe irritated skin.

- Calamine lotion is a topical medication used to relieve itching and discomfort associated with Poison Ivy, Oak, and Sumac rashes.